Peer Reviewed Publications
Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques.
Kent SJ, De Rose R, Mokhonov VV, Mokhonova EI, Fernandez CS, Alcantara S, Rollman E, Mason RD, Loh L, Peut V, Reece JC, Wang XJ, Wilson KM, Suhrbier A, Khromykh A.
Department of Microbiology and Immunology, University of Melbourne, 3010, Australia.
Virology. 2008 May 10; 374 (2):528-34. Epub 2008 Feb 12.
Control of viremia and prevention of AIDS following immunotherapy of SIV-infected macaques with peptide-pulsed blood.
De Rose R, Fernandez CS, Smith MZ, Batten CJ, Alcāntara S, Peut V, Rollman E, Loh L, Mason RD, Wilson K, Law MG, Handley AJ, Kent SJ.
Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.
PLoS Pathog. 2008 May 2;4 (5):e1000055.
Evaluation of Eight Anti-rubella Immunoglobulin G Immunoassays that Report Results in International Units per Milliliter.
Dimech W, Panagiotopoulos L, Francis B, Laven N, Marler J, Dickeson D, Panayotou T, Wilson K, Wootten R, Dax EM.
National Serology Reference Laboratory, Australia, St. Vincent's Institute, 4th Floor, Healy Building, 41 Victoria Parade, Fitzroy 3065, Department of Serology, Symbion Health, Dorevitch Pathology, 18 Banksia Street, Heidelberg 3084, Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead 2145, Microbiology Department, Southern Health, 246 Clayton Road, Clayton 3168, Department of Microbiology and Immunology, University of Melbourne, Parkville, 3052, Australia.
J Clin Microbiol. 2008 Apr 23 [Epub ahead of print]
Assessing Interpretation Proficiency of Rapid HIV Assays in Non-Laboratory Settings: Ensuring the Quality of Testing.
Learmonth KM, McPhee DA, Jardine DK, Walker SK, Aye TT, Dax EM.
National Serology Reference Laboratory, Australia, St Vincent's Institute, Fitzroy, Victoria, Australia; Department of Medicine at St Vincent's Health, University of Melbourne, Fitzroy, Victoria, Australia; Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.
J Clin Microbiol. 2008 Mar 19 [Epub ahead of print].
Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.
Gorry PR, McPhee DA, Verity E, Dyer WB, Wesselingh SL, Learmont J, Sullivan JS, Roche M, Zaunders JJ, Gabuzda D, Crowe SM, Mills J, Lewin SR, Brew BJ, Cunningham AL, Churchill MJ.
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.
Retrovirology. 2007 Sep 23; 4:66.
Viral Phenotypes and Antibody Responses in Long-Term Survivors Infected with Attenuated Human Immunodeficiency Virus Type 1 Containing Deletions in the nef and Long Terminal Repeat Regions
E E Verity, D Zotos, K Wilson, C Chatfield, V A Lawson, D E Dwyer, A Cunningham, J Learmont, W Dyer, J Sullivan, P R Gorry and D A McPhee
Department of Microbiology, Monash University, Clayton, Victoria, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, National Serology Reference Laboratory, Australia, St Vincent's Institute, Fitzroy, Victoria, Australia, School of Biological and Chemical Sciences, Deakin University, Burwood, Victoria, Australia, Centre for Virus Research, Westmead Millenium Institute, Westmead, New South Wales, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Dana-Farber Cancer Institute, Boston, Massachusetts and Department of Neurology, Havard Medical School, Boston, Massachusetts
Journal of Virology 81 (17) 9268-9278 Sep 2007
The Heterosexual HIV Type 1 Epidemic in Papua New Guinea is Dominated by Subtype C
C E Ryan, J Gare, S M Crowe, K Wilson, J C Reeder and R B Oelrichs
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Papua New Guinea Institute for Medical Research, Goroka, PNG,
National Serology Reference Laboratory, Australia, Melbourne, Victoria, Australia, Global HIV/AIDS Program, The World Bank, Washington, D.C. USA, C.E.R. and J.G. contributed equally to this work.
AIDS Research and Human Retroviruses 23 (7) 941-944 Jul 2007
Phenotype and Envelope Gene Diversity of nef-deleted HIV-1 Isolated from Long-Term Survivors Infected from a Single Source
L Gray, M J Churchill, J Sterjovski, K Witlox, J C Learmont, J S Sullivan, S L Wesselingh, D Gabuzda, A L Cunningham, D A McPhee and P R Gorry
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Department of Pathology and Immunology, Monash University, Melbourne, Victoria, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia, Dana-Farber Cancer Institute, Boston, MA, USA, Department of Neurology, Harvard Medical School, Boston, MA, USA, Westmead Millennium Institute, Westmead, New South Wales, Australia, National Serology Reference Laboratory, Australia and St. Vincent's Institute for Medical Research, Fitzroy, Victoria, Australia
Virology Journal 4 (75) Jul 2007
Macrophage Tropism and Cytopathicity of HIV-1 Variants Isolated Sequentially from a Long-Term Survivor Infected with nef-Deleted Virus
P R Gorry, D A McPhee, S L Wesselingh and M J Churchill
Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Department of Medicine, Monash University, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia, National Serology Reference Laboratory, Fitzroy, Victoria, Australia, St. Vincent's Institute, Fitzroy, Victoria, Australia
The Open Microbiology Journal 1 (7) 1-7 Jun 2007
The Prevalence and risk behavious associated with the transmission of blood-borne viruses among ethnic-Vietnamese injecting drug users
M E Hellard, O K Nguyen, R J Guy, D Jardine, A Mijch, P G Higgs
Centre for Epidemiology and Population Health Research, Macfarlane Burnet Institute for Medical Research and Public Health, Victoria, Department of Epidemiology and Preventive Medicine, Monash University, Victoria, National Serology Reference Laboratory, Australia, Victorian HIV/AIDS Service, Infectious Disease Unit, Alfred Hospital, Victoria
Australian and New Zealand Journal of Public Health 30 (6) 519-525 Nov 2006
HIV Testing in 2006: issues and methods
D Chang, EM Dax and K Learmonth
National Serology Reference Laboratory, Australia
Expert Review of Anti-infective Therapy 4 (4):565-582 Aug 2006
Comparative Evaluation of Simian, Simian-Human, and Human Immunodeficiency Virus Infections in the Pigtail Macaque (Macaca nemestrina) Model
C J Batten, R De Rose, K M Wilson, M B Agy, S chea, I Stratov, D C Montefiori and S J Kent
Department of Microbiology and Immunology, University of Melbourne, Victoria, Australia, National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, Washington Regional Primate Research Center, University of Washington, Seattle, Washington, USA and Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
AIDS Research and Human Retroviruses 22 (6) 580-588 June 2006
Transcriptional activity of blood- and cerebrospinal fluid-derived nef/long-terminal repeat sequences isolated from a slow progressor infected with nef-deleted human immunodeficiency virus type 1 (HIV-1) who developed HIV-associated dementia
M J Churchill, A Figueiredo, D Cowley, L Gray, D F J Purcell, J S Sullivan, D A McPhee, S L Wesselingh, B J Brow and P R Gorry
Macfarland Burnet Institute of Medical Research and Public Health, Melbourne, Victoria, Australia, Departments of Microbiology and Medicine, Monash University, Melbourne, Victoria, Australia, Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia, Australian Red Cross Blood Service, Sydney, New South Wales, Australia, Faculty of Medicine, University of Sydney, New South Wales, Australia, National Serology Reference Laboratory, Australia, St. Vincent's Institute for Medical Research, Fitzroy, Victoria, Australia and Department of Neurology, St. Vincent's Hospital, Darlinghurst, New South Wales, Australia
Journal of NeuroVirology 12 219-228 May 2006
Point of care using simple/rapid HIV tests
K Learmonth, D McPhee and E M Dax
National Serology Reference Laboratory, Australia
Microbiology Australia 82-83 May 2006
Humoral Immune Response to Primary Rubella Infection
K M Wilson, C Di Camillo, L Doughty and E M Dax
National Serology Reference Laboratory, Australia
Clinical & Vaccine Immunology 13 (3):380-386 2006
Broad neutralisation and complement-mediated lysis of HIV-1 by PEHRG214, a novel caprine anti-HIV polyclonal antibody
E E Verity, L A Williams, D Haddad, V Choy, C O'Loughlin, C Chatfield, N Saksena, A Cunningham, F Gelder and D A McPhee
Department of Microbiology, Monash University, clayton, Victoria, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, Virionyx Corporation, Auckland, New Zealand, National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, National Centre in HIV Virology Research, Melbourne, Victoria, Australia, Retroviral Genetics Division, Westmead Millenium Institute, Sydney, New South Wales, Australia
AIDS 20 (4):505-515 2006
Calculating Uncertainty of measurement for Serology Assays by Use of Precision and Bias
W Dimech, B Francis, J Kox and G Roberts
National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia; National Association of Testing Authorities, North Melbourne, Victoria, Australia;
Clinical Chemistry 52 (3) 526-529 Jan 2006
Use of Participant EQA Results to Assess Sample Homogeneity and Stability for Qualitative Analytes
D Tholen, R Chappel and B Francis
Dan Tholen Statistical Consulting Services, Michigan, USA and National Serology Reference Laboratory, Australia
Accred. Qual. Assur. 11 (8-9) 400-407 Aug 2006
Commercial Enzyme immunoassay Adapted for the Detection of Antibodies to Hepatitis C Virus in Dried Blood Spots
H A Croom, K M Richards, S J Best, B H Francis, E I M Johnson, E M Dax and K M Wilson
National Serology Reference Laboratory, Australia
Journal of Clinical Virology 36 68-71 2006
Advances in Transfusion Safety - Vol. 4
E M Dax, A Farrugia and G N Vyas
National Serology Reference Laboratory, Victoria, Australia, Therapeutic Good Administration, ACT, Australia, The Medical Center, University of California, San Francisco, California, USA
International Conference, Sydney, October 2005: Proceedings, Book 2007
Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3
S J Kent, C J Dale, C Ranasinghe, I Stratov, R De Rose, S Chea, D C Montefiori, S Thomson, I A Ramshaw, B E Coupar, D B Boyle, M Law, K M Wilson, A J Ramsay
Department of Microbiology and Immunology, University of Melbourne, Vic., Australia, National Serology Reference Laboratory, Fitzroy, Vic., Australia
Vaccine 23 (42):5009-21 2005
Evaluation of three immunoassays used for detection of anti-rubella virus immunoglobulin M antibodies
W Dimech, L Panagiotopoulos, J Marler, N Laven, S Leeson, E M Dax
National Serology Reference Laboratory, Australia, Fitzroy, Victoria, Australia, Department of Serology, Mayne Health, Dorevitch Pathology, Heidelberg, Victoria, Australia, Department of Serology, Mayne Health, Laverty Pathology, North Ryde, NSW, Australia
Clin Diagn Lab Immunol. 12 (9):1104-8 Sep 2005
Subtype AE HIV-1 DNA and recombinant Fowlpoxvirus vaccines encoding 5 shared HIV-1 genes: safety and T cell immunogenicity in macaques
R De Rose, S Chea, CJ Dale, J Reece, CS Fernandez, KM Wilson, S Thomson, IA Ramshaw, BEH Coupar, DB Boyle, MT Sullivan & SJ Kent
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Vic., Australia
Vaccine 23 (16):1949-1956 2005
A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibody, HRG214, in HIV-1 infected individuals
S L Pett, L A Williams, R O Day, A R Lloyd, A D Carr, K R Clezy, S Emery, E Kaplan, D A McPhee, A J McLachlan, F B Gelder, S R Lewin, W Liauw, K M Williams
HIV Clin Trials 5 (2):91-8 2004
Longitudinal Analysis of nef/LTR-deleted HIV-1 in Blood and CSF of a Long-Term Survivor who developed HIV-Associated Dementia
M Churchill, J Sterjovski, L Gray, D Cowley, C Chatfield, J Learmont, J S Sullivan, S M Crowe, B J Brew, S L Wesselingh D A McPhee and P R Gorry
National Serology Reference Laboratory, Australia, Macfarlane Burnet Institute for Medical Research and Public Health, Department of Medicine, Monash University, Melbourne, Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia, Australian Red Cross Blood Service, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia and St. Vincent's Hospital, Darlinghurst, NSW, Australia
Journal of Infectious Diseases 190 2181-6 Dec 2004
Apoptosis induced in synchronized human immunodeficiency virus type 1 infected primary peripheral blood mononuclear cells is detected after the peak of CD4+ T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein
V A Lawson, K A Silburn, P R Gorry, G Paukovic, D F J Purcell, A L Greenway, D A McPhee
Virology 327 70-82 2004
Advances in laboratory testing for HIV
E M Dax & A Arnott
National Serology Reference Laboratory, Fitzroy, Vic., Australia;
Pathology 36 (6):551-560 2004
Incidence Immunoassay for Distinguishing Recent from Established HIV-1 Infection in Therapy Naive Populations
KM Wilson, EIM Johnson, HA Croom, KM Richards, L Doughty, PH Cunningham, BE Kemp, BM Branson & EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia;
AIDS 18 (17):2253-2259 2004
Evaluation in macaques of HIV-1 DNA vaccines containing CpG motifs and fowlpoxvirus vaccines co-expressing IFNg or IL-12
CJ Dale, R De Rose, KM Wilson, HA Croom, S Thomson, BEH Coupar, A Ramsay, DFJ Purcell, R French, M Law, S Emery, DA Cooper, IA Ramshaw, DB Boyle & SJ Kent for the Australia; Australian Thai HIV Vaccine Consortium
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Vic., Australia
Vaccine 23 (2):188-197 2004
Impact of Proficiency Testing for the Microscopic Agglutination Test for Leptospirosis
RJ Chappel, M. Goris, MF Palmer and RA Hartskeerl
National Serology Reference Laboratory, Fitzroy, Vic., Australia; Leptospirosis Reference Centre (WHO/FAO/OIE), Royal Tropical Institute, Amsterdam, The Netherlands; Leptospira Reference Unit, County Hospital, Hereford , UK.
J. Clin. Microbiol. 42 (12):5484-5488 2004
Continuing education in clinical microbiology: a survey to determine scientists' attitude to existing programmes
W Dimech and D Grando
National Serology Reference Laboratory, Fitzroy, Vic., Australia; RMIT University, Melbourne, Australia
Australian Journal of Medical Science 25 (3):129-139 2004
Comprehensive quality control programme for serology and nucleic acid testing using an internet-based application
W Dimech, S Walker, D Jardine, S Read, K Smeh, M Karakaltsas, B Dent and EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia
Accred. Qual. Assur. 9 148-151 2004
Validation of assembled nucleic acid-based tests in diagnostic microbiology laboratories
W Dimech, DS Bowden, B Brestovac, K Byron, G James, D Jardine, T Sloots and EM Dax
National Serology Reference Laboratory, Fitzroy, Vic., Australia
Pathology 36 (1):45-50, 2004
External Quality Assessment Schemes and Their Value to Blood Services
EM Dax
National Serology Reference Laboratory, Australia
Indian J. Hemat & Blood Transf. Vol. XXI: Suppl 3 66-68 2003
New precision in measuring trachoma infection
HR Taylor, EM Dax
Centre for Eye Research Australia, University of Melbourne, East 3002, Melbourne, Australia
Lancet 362 (9379):181-182 2003
Calibration of HIV-1 working reagents for nucleic acid amplification techniques against the 1st international standard for HIV-1 RNA
C Davis, A Heath, S Best, I Hewlett, N Lelie, R Schuurman and H Holmes
Division of Retrovirology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, UK
J. Virological Methods 107 (1):37-44 2003
A Quality Assessment Program (QAP) for Genotypic Antiretroviral Testing (GART) Results in an improvement in the detection of drug resistance mutations
DC Sayer, S Land, L Gizzarelli, M French, G Hales, S Emery, EM Dax and FT Christiansen
Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Perth 6000, Western Australia, Australia
J. Clin. Micro. 41 (1):227-236 2003
Anti-HCV conformity testing of voluntary blood donors: comparison of the sensitivity of two immunoblot assays
P Kiely, L Eliades, M Kebede, M Stephenson and D Jardine
Virus Serology Unit, Australian Red Cross Blood Service-Victoria, South Melbourne
Transfusion 42(8):1053-1058 2002
Sensitivity of HCV-RNA and HIV-RNA blood screening assays
PN Lelie, AAJ van Drimmelen, HTM Cuypers, SJ Best , SL Stramer, C Hyland, JP Allain, P Moncharmont, C Defer, M Nubling, A Glauser, M da Silva Cardoso,
JF Viret, M Lankinen, L Grillner, U Wirthmuller, V Coste, B Masecar and EM Dax
VQC Laboratory, Sanquin-CLB Diagnostic Division, Amsterdam, The Netherlands.
Transfusion, 42(5):527-536 2002
Underestimation of HIV type 1 drug resistance mutations: results from the ENVA-2 genotyping proficiency program
R Schuurman, D Brambilla, T de Groot, D Huang, S Land, J Bremer, I Benders and CA Boucher
Department of Virology, University Medical Center Utrecht, The Netherlands
AIDS Research and Human Retrovirus Journal, Vol 18 (4) 243-248 2002
Variant Creutzfeldt-Jakob disease in Australian blood donors: estimation of risk and the impact of deferral strategies
P Correll, MG Law, C Seed, A Gust, M Buring, EM Dax, A Keller and JM Kaldor
National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia.
Vox Sang, Vol 81 6-11 2001
External Quality Assessment program for Chlamydia trachomatis Diagnostic testing by Nucleic Acid Amplification Assays
S Land, S Tabrizi, A Gust, E Johnson, S Garland and E.M Dax
National Serology Reference Laboratory, Australia & Royal Women's Hospital
J. Clin. Micro. 40 (8). 2893-2896, August 2002
Specific Antibody Responses to an HIV-1 Vaccine
A.R.Sands, S.J.Kent, E.M.Dax and E.I.M. Johnson
National Serology Reference Laboratory, Australia, Department of Microbiology and Immunology,
University of Melbourne, Parkville, Australia
(Proceedings of the 6th European Conference on Experimental AIDS Research, Edinburgh, UK, 23-26th June, 2001).
Anti-HIV Quality Assurance Programs in Australia and the Southeast Asian and Western Pacific Regions
Gust A, Walker S, Chappel R.J and Dax E.M
National Serology Reference Laboratory, Australia
Accred. Qual. Assur. 6 168-172
New Leptospires Infecting Australian Pigs
R.J.Chappel, S.D. Driesen, K.A. Moore, D.A. Khalik
National Serology Reference Laboratory, Australia, Victorian Institute of Animal Science
Australian Association of Pig Veterinarians, Melbourne Proceedings 2001, pp 5-8, 14 May 2001
Quality and Laboratory Diagnosis of HIV Infection
Christopher W. Hamilton & Elizabeth M. Dax
National Serology Reference Laboratory, Australia
Microbiol Australia, Vol 22 (1) 2001